Efficacy of different ways of cocktail analgesic mixture injection on total knee arthroplasty.
10.11817/j.issn.1672-7347.2020.180801
- Author:
Kewei LI
1
;
Yingzhou HOU
2
;
Shaohua WANG
2
;
Zhihong LI
3
Author Information
1. Second Department of Joint Disease, Zhengzhou Orthopedics Hospital, Zhengzhou 450052. lkw0903@163.com.
2. Second Department of Joint Disease, Zhengzhou Orthopedics Hospital, Zhengzhou 450052.
3. Department of Orthopedics, Second Xiangya Hospital, Central South University, Changsha 410011, China. lizhihong@csu.edu.cn.
- Publication Type:Journal Article
- Keywords:
analgesia;
anterior intra-articular injection;
cocktail therapy;
posterior intra-articular injection;
total knee arthroplasty
- MeSH:
Analgesics;
Arthroplasty, Replacement, Knee;
Humans;
Injections, Intra-Articular;
Osteoarthritis, Knee;
surgery;
Pain Measurement;
Pain, Postoperative;
prevention & control
- From:
Journal of Central South University(Medical Sciences)
2020;45(4):406-410
- CountryChina
- Language:English
-
Abstract:
OBJECTIVES:To evaluate the efficacy of different ways of cocktail analgesic mixture injection on total knee arthroplasty (TKA).
METHODS:A total of 50 patients with knee osteoarthritis treated by TKA from July to September 2018 were randomly divided into two groups (=25). The Group 1 underwent anterior intra-articular injection before prosthesis implanted while the Group 2 underwent posterior intra-articular injection before prosthesis implanted. Visual Analogue Scale (VAS) of all patients for pain during activity and at rest, maximal flexion degree of the knee at the 48th h and the 72th h after surgery, the time of raise leg, usage rate of patient-controlled analgesia (PCA), and complications were evaluated and analyzed.
RESULTS:VAS for pain at rest of patients in the Group 1 was significantly less than that in the Group 2 at the 6th, 12th, and 24th h after surgery (all <0.05). Maximal flexion degree of the knee at the 48th h and the 72th h after surgery in the Group 1 was better than that in the Group 2 (both <0.05). The Group 1 costed less time than the Group 2 on the ability to perform an active straight leg raise (=0.027).
CONCLUSIONS:The anterior intra-articular cocktail analgesic mixture injection can strongly relieve the pain early after TKA, which can improve knee function and achieve painless rehabilitation in most patients, with safety.
