Advances in study on exosomes and their applications in kidney diseases.
10.11817/j.issn.1672-7347.2020.190110
- Author:
Can CHEN
1
;
Meichu CHENG
2
Author Information
1. Department of Nephrology, Second Xiangya Hospital, Central South University, Changsha 410011. 2576796992@qq.com.
2. Department of Nephrology, Second Xiangya Hospital, Central South University, Changsha 410011. 766076183@qq.com.
- Publication Type:Journal Article
- Keywords:
biomarkers;
exosomes;
kidney diseases
- MeSH:
Biomarkers;
Cell Communication;
Exosomes;
Humans;
Kidney Diseases;
Proteins
- From:
Journal of Central South University(Medical Sciences)
2020;45(4):440-448
- CountryChina
- Language:English
-
Abstract:
Exosomes are in a size of 30-100 nm vesicles released by various cells, with a double-layered lipid membrane containing DNA, RNA, and protein. In the past, exosomes were considered to be molecular waste, and recently exosomes have been shown to be involved in many pathophysiological processes, including intercellular communication, immune response, nerve repair, and tumorigenesis. Exosomes are present in numerous body fluids, and urinary exosomes have been shown to be biomarkers of a variety of kidney diseases.
