Dapsone in a Case with Chronic Recurrent Henoch-Sch nlein Purpura.
- Author:
Jin CHOI
1
;
Soo Jung LEE
;
Dae Kyun KOH
Author Information
1. Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Henoch-Sch nlein Purpura;
Leukocytoclastic vasculitis;
Dapsone
- MeSH:
Adolescent;
Adrenal Cortex Hormones;
Dapsone*;
Female;
Humans;
Neutrophils;
Purpura*;
Skin Manifestations;
Vasculitis;
Vasculitis, Leukocytoclastic, Cutaneous
- From:Journal of the Korean Pediatric Society
1999;42(11):1574-1578
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The most clearly delineated condition with prominent cutaneous leukocytoclastic vasculitis which presents to a pediatrician is Henoch-Sch nlein purpura. There is general agreement that in Henoch-Sch nlein syndrome the skin manifestations have a very benign long-term course and that corticosteroids are of little value. Dapsone appears to be of special value in diseases characterized by an accumulation of polymorphonuclear neutrophils notably leukocytoclastic vasculitis. In the pediatric literature, however, no information is available on the use of this sulfone in Henoch-Sch nlein purpura. We report a case of Henoch-Sch nlein purpura in a 14-year-old female patient who presented with chronic recurrent skin manifestation and responded to dapsone for two years.
