Rubus chingii Hu: an overview of botany, traditional uses, phytochemistry, and pharmacology.
10.1016/S1875-5364(20)30048-0
- Author:
Jia-Yun SHENG
1
;
Si-Qi WANG
1
;
Kao-Hua LIU
1
;
Bo ZHU
1
;
Qiao-Yan ZHANG
1
;
Lu-Ping QIN
2
;
Jian-Jun WU
3
Author Information
1. School of Pharmacy, Zhejiang Chinese Medical University, Hangzhou 310053, China.
2. School of Pharmacy, Zhejiang Chinese Medical University, Hangzhou 310053, China. Electronic address: lpqin@zcmu.edu.cn.
3. School of Pharmacy, Zhejiang Chinese Medical University, Hangzhou 310053, China. Electronic address: wjjpharmacy@163.com.
- Publication Type:Journal Article
- Keywords:
Botany;
Pharmacology;
Phytochemistry;
Review;
Rubus chingii Hu;
Traditional uses
- From:
Chinese Journal of Natural Medicines (English Ed.)
2020;18(6):401-416
- CountryChina
- Language:English
-
Abstract:
Rubus chingii Hu, a member of the rosaceae family, is extensively distributed in China and Japan. Its unripe fruits (Fupenzi in Chinese) have a long history of use as an herbal tonic in traditional Chinese medicine for treating various diseases commonly associated with kidney deficiency, and they are still in use today. Phytochemical investigations on the fruits and leaves of R. chingii indicate the presence of terpenoids, flavonoids, steroids, alkaloids, phenylpropanoids, phenolics, and organic acids. Extracts or active substances from this plant are reported to have various pharmacological properties, including antioxidant, anti-inflammatory, antitumor, antifungal, antithrombotic, antiosteoporotic, hypoglycemic, and central nervous system-regulating effects. This review provides up-to-date information on the botanical characterizations, traditional usages, chemical constituents, pharmacological activities, toxicity, and quality control of R. chingii. Possible directions for future research are also briefly proposed. This review aims to supply fundamental data for the further study of R. chingii and contribute to the development of its clinical use.
