Progress in engineering application of human adenovirus.

Author: Yang ZHAO ¹ ; Qiwei ZHANG ² ; Xueshan XIA ¹
Author Information

1. Yunnan Provincial Center for Molecular Diagnosis, Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, Yunnan, China.
2. College of Public Health, Southern Medical University, Guangzhou 510515, Guangdong, China.
Publication Type:Journal Article
Keywords: engineering application; human adenovirus; oncolytic; vector
MeSH: Adenovirus Infections, Human; epidemiology; virology; Adenoviruses, Human; genetics; Genetic Engineering; methods; trends; Genetic Vectors; Humans; Oncolytic Virotherapy; trends; Oncolytic Viruses; genetics; Virus Replication
From: Chinese Journal of Biotechnology 2020;36(7):1269-1276
CountryChina
Language:Chinese
Abstract: Human adenoviruses are widespread causative agent that induces respiratory diseases, epidemic keratoconjunctivitis and other related diseases. Adenoviruses are commonly used in experimental and clinical areas. It is one of the most commonly used virus vectors in gene therapy, and it has attracted a lot of attention and has a high research potential in tumor gene therapy and virus oncolytic. Here, we summarize the biological characteristics, epidemiology and current application of adenovirus, in order to provide reference for engineering application of adenovirus.