A Case of Gastroesophageal Amyloidosis with Upper Gastrointestinal Bleeding in a Patient with Multiple Myeloma.
- Author:
Sang Ok LEE
1
;
Young Sook LEE
;
Sung Hee JUNG
;
Yun Jung LEE
;
Hoon GO
;
Gi Young CHOI
;
Anna KIM
;
Hyeon Woong YANG
;
Sang Woo CHA
;
Seong Ho KIM
;
Sung Soo CHANG
Author Information
1. Department of Internal Medicine, Eulji University School of Medicine, Eulji University Hospital, Daejeon, Korea. jsh@eulji.ac.kr
- Publication Type:Case Report
- Keywords:
Amyloidosis;
Multiple myeloma;
Gastrointestinal hemorrhage;
Stomach;
Esophagus
- MeSH:
Abdominal Pain;
Amyloidosis*;
Colon;
Diarrhea;
Duodenum;
Esophagus;
Gastrointestinal Hemorrhage;
Gastrointestinal Tract;
Heart;
Hemorrhage*;
Humans;
Intestinal Pseudo-Obstruction;
Intestine, Small;
Kidney;
Liver;
Multiple Myeloma*;
Nervous System;
Rectum;
Skin;
Stomach;
Vomiting
- From:Korean Journal of Gastrointestinal Endoscopy
2007;34(5):263-268
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Amyloidoses are disorders for which homogeneous amorphous fibrillar proteins accumulate in multiple organs. These diseases are classified into systemic and localized disease by their extent, the primary disease and their association with multiple myeloma, and the secondary and familial disease are classified by their association with the underlying diseases. Amyloidoses can develop in association with multiple myeloma, but only rare cases have been reported on that involve the gastroesophageal tract. Amyloidosis can involve the kidney, heart, liver, skin, gastrointestinal tract and nervous system, and they can involve the small intestine, duodenum, stomach, colon, rectum and esophagus when there is disease of the gastrointestinal tract. We may overlook gastrointestinal involvement of amyloidoses if there are few symptoms and laboratory abnormalities because of the diverse clinical courses and features. Amyloidoses can manifest abdominal pain, diarrhea, vomiting and perforation, but gastrointestinal hemorrhages are rare. We report here on a case of gastroesophageal amyloidosis with upper gastrointestinal hemorrhage and paralytic ileus due to multiple myeloma.
