Chest High-resolution Computed Tomography Imaging Features of Lung Involvement in Rheumatoid Arthritis.
10.3881/j.issn.1000-503X.12357
- Author:
Lan SONG
1
;
Hua-Yang DU
1
;
Ru-Xuan CHEN
2
;
Xin SUI
1
;
Wei SONG
1
;
Zheng-Yu JIN
1
Author Information
1. Department of Radiology, PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
2. Department of Rheumatology and Clinical Immunology, PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
- Publication Type:Journal Article
- Keywords:
X-ray computed;
high-resolution;
imaging finding;
pulmonary lesions;
rheumatoid arthritis;
tomography
- MeSH:
Adolescent;
Adult;
Aged;
Aged, 80 and over;
Arthritis, Rheumatoid;
complications;
diagnostic imaging;
Female;
Humans;
Lung;
Lung Diseases, Interstitial;
diagnostic imaging;
etiology;
Male;
Middle Aged;
Retrospective Studies;
Tomography, X-Ray Computed;
Young Adult
- From:
Acta Academiae Medicinae Sinicae
2020;42(2):202-208
- CountryChina
- Language:Chinese
-
Abstract:
To explore the chest high-resolution computed tomography (HRCT) features in patients with rheumatoid arthritis (RA) complicated with pulmonary involvement. Totally 161 patients with RA with lung involvement were collected from June 2014 to May 2018. The chest HRCT findings were retrospectively analyzed. According to the imaging features as well as the results of history taking,pulmonary function test,pathology,and bronchoalveolar lavage fluid test,RA-related lung diseases (RA-LD) were classified and their clinical characteristics were compared. These 161 RA-LD patients (56 males and 105 females) whose mean age at diagnosis was (60.7±12.8) years (14-85 years) included 87 cases of usual interstitial pneumonia (UIP) (including 16 cases of possible UIP),44 cases of non-specific interstitial pneumonia (NSIP),10 cases of organizing pneumonia,7 cases of lymphocytic interstitial pneumonia,9 cases of small airway disease (SAD) (including 8 cases of bronchiolitis obliterans and 1 case of follicular bronchiolitis),and 4 other lung manifestations (including 3 cases of diffuse alveolar hemorrhage and 1 case of rheumatoid nodules). The UIP group had the oldest average age [(63.3±12.1) years old] and the highest smoking rate (41.4%). The SAD group had the youngest average age [(54.7±15.1) years old] and there was no smoking history. There were significant differences between these two groups (=0.020,<0.001). Seventy patients (43.5%) with RA-LD were complicated with pleural lesions. RA involving the lung is common and has varied imaging manifestations,with interstitial lung diseases (mainly UIP and NSIP) being the most important manifestations. RA patients should undergo lung HRCT as early as possible to identify the lung involvement and related types.