Value of Thermal Tomography in Early Diagnosis of Breast Cancer in Animal Models.
10.3881/j.issn.1000-503X.11988
- Author:
Xiao-Wei XUE
1
;
Jun-Lai LI
1
;
Shao-Wei XUE
2
;
Cheng ZHANG
1
Author Information
1. Department of Ultrasound,the Second Medical Center, Chinese PLA General Hospital,Beijing 100853,China.
2. Department of Ultrasound, the First Medical Center,Chinese PLA General Hospital,Beijing 100853,China.
- Publication Type:Journal Article
- Keywords:
breast cancer;
thermal tomography;
ultrasound
- MeSH:
Animals;
Breast Neoplasms;
diagnostic imaging;
Early Diagnosis;
Mice;
Mice, Inbred NOD;
Mice, SCID;
Neoplasms, Experimental;
diagnostic imaging;
Rats;
Rats, Sprague-Dawley;
Tomography;
Ultrasonography, Mammary
- From:
Acta Academiae Medicinae Sinicae
2020;42(2):236-241
- CountryChina
- Language:Chinese
-
Abstract:
To obtain ultrasound and thermal tomography images of breast cancer during its growth and to assess the value of thermal tomography in detecting breast cancer. Breast cancer models were established with NOD/SCID mice and SD rats. These animal models were examined by thermal tomography,plain ultrasound,and contrast-enhanced ultrasound. Tumor tissues were stained with CD34 to explore the relationship between tumor heat production and vascular pathology. Thermal tomography detected breast cancer 2-4 days earlier than ultrasound. The expression of CD34 in tumor tissues was increased,along with thickened,increased,and irregular blood vessels. Thermal tomography can detect early breast cancer and is a promising tool for screening breast cancer.
