Roles of Platelet Toll-like Receptors in Thrombosis.
10.3881/j.issn.1000-503X.11257
- Author:
Jie CAO
1
;
Renqiang YANG
1
Author Information
1. Department of Cardiology,Second Affiliated Hospital of Nanchang University,Nanchang 330006,China.
- Publication Type:Journal Article
- Keywords:
Toll-like receptors;
platelets;
thrombosis
- MeSH:
Blood Platelets;
Hemostasis;
Humans;
Platelet Activation;
Thrombosis;
Toll-Like Receptors
- From:
Acta Academiae Medicinae Sinicae
2020;42(3):388-392
- CountryChina
- Language:Chinese
-
Abstract:
Platelets are non-nuclear blood cells that are widely involved in physiological and pathological processes.Their main role is to participate in hemostasis and thrombosis.Toll-like receptors(TLRs)are innate immune receptors.Platelets express multiple TLRs and can promote thrombosis by recognizing ligand-induced platelet activation and aggregation.This article reviews the relationship between platelets/TLR and thrombosis and the roles of TLRs in the development of thrombotic diseases.
