Research Advances in the Association between Inflammasome and Abdominal Aortic Aneurysm.
10.3881/j.issn.1000-503X.11089
- Author:
Lei JI
1
;
Fangda LI
1
;
Yuehong ZHENG
1
Author Information
1. Department of Vascular Surgery,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
- Publication Type:Journal Article
- Keywords:
abdominal aortic aneurysm;
inflammasome;
inflammation
- MeSH:
Aortic Aneurysm, Abdominal;
Humans;
Inflammasomes;
Inflammation;
Interleukin-1beta;
NLR Family, Pyrin Domain-Containing 3 Protein
- From:
Acta Academiae Medicinae Sinicae
2020;42(3):393-398
- CountryChina
- Language:Chinese
-
Abstract:
The inflammasome is a multiprotein complex localized in the cytoplasm.It can mediate the expressions of various inflammatory cytokines such as interleukin(IL)-1β and IL-18 and plays a key role in regulating inflammatory response.As sterile inflammation,abdominal aortic aneurysm currently can only be treated by surgery.This article reviews the research advances in the role of inflammasomes in abdominal aortic aneurysm.
