Application of Raman Spectroscopy in the Diagnosis of Oral Cancer.
10.3881/j.issn.1000-503X.11270
- Author:
Zhihui ZHU
1
;
Fanhao MENG
1
;
Jiabin XIA
2
;
Xiaofeng XU
2
;
Yang HU
2
;
Aijin ZHANG
1
;
Tao ZHANG
1
Author Information
1. Department of Stomatology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
2. Key Laboratory of the Ministry of Education for Optoelectronic Measurement Technology and Instrument, Beijing Information Science & Technology University,Beijing 100192,China.
- Publication Type:Journal Article
- Keywords:
Raman spectrum;
diagnosis;
molecular fingerprint;
oral cancer
- MeSH:
Humans;
Mouth Neoplasms;
Spectrum Analysis, Raman
- From:
Acta Academiae Medicinae Sinicae
2020;42(3):399-404
- CountryChina
- Language:Chinese
-
Abstract:
Oral cancer is a common and deadly malignancy.While multidisciplinary treatment(mainly surgery)has been applied in the treatment of cancer treatment,early diagnosis and complete removal of the primary lesion are essential for a better prognosis.Raman spectroscopy is an optical technique that detects inelastic scattered light generated by the interaction of light and matter.It can detect the vibrational spectra of biochemical and biomolecular structures and tissue conformations,and can provide the "molecular fingerprint" for cells,tissues,and biological fluids.With the development of related technologies and optical instruments,Raman spectroscopy has been widely applied in medical fields.This article reviews the research advances and application of Raman spectroscopy in the diagnosis of oral cancer.
