Cryptococcal Encephalitis Complicating Anti-N-methyl-D-aspartate Receptor Encephalitis in an Immunosuppressed Patient.
10.3881/j.issn.1000-503X.11472
- Author:
Dongming LIU
1
;
Hongwei XU
1
;
Fang YI
1
Author Information
1. Department of Geriatric Neurology,Xiangya Hospital,Central South University,Changsha 410008,China.
- Publication Type:Case Reports
- Keywords:
anti-N-methyl-D-aspartate receptor encephalitis;
coexist;
cryptococcal encephalitis;
immunosuppressed
- MeSH:
Anti-N-Methyl-D-Aspartate Receptor Encephalitis;
Antibodies;
Humans;
Receptors, N-Methyl-D-Aspartate
- From:
Acta Academiae Medicinae Sinicae
2020;42(3):417-420
- CountryChina
- Language:Chinese
-
Abstract:
Cryptococcal encephalitis is a fatal central nervous system infectious disease,whereas anti-N-methyl-D-aspartate(NMDA)receptor encephalitis(NMDARE)is an autoimmune syndrome associated with psychological symptoms,behavioural abnormalities,seizures,and dyskinesias.Despite their distinct pathologies and pathogenic mechanisms,both of them can lead to cognitive dysfunction and abnormal behaviors,although anti-NMDARE can also have mood and mental disorders as its core manifestations.A patient with nephrotic syndrome accompanied by both cryptococcal encephalitis and anti-NMDARE was treated in our center,which for the first confirmed that these two conditions could coexist in one patient.The underlying mechanism may be similar to that of anti-NMDARE after other infections.
