Signaling Pathways in the Pathogenesis of Acne Vulgaris.
10.3881/j.issn.1000-503X.11470
- Author:
Hong-Yan TANG
1
;
Bin XIAO
1
;
Xin LIU
1
;
Gui-Lan YANG
2
Author Information
1. Department of Dermatology,the Second Affiliated Hospital of Lanzhou University,Lanzhou 730000,China.
2. Department of Dermatology,Shenzhen Hospital of Southern Medical University,Shenzhen,Guangdong 518000,China.
- Publication Type:Journal Article
- Keywords:
acne vulgaris;
pathogenesis;
signaling pathways
- MeSH:
Acne Vulgaris;
Adolescent;
Humans;
Sebaceous Glands;
Sebum;
Signal Transduction
- From:
Acta Academiae Medicinae Sinicae
2020;42(4):559-561
- CountryChina
- Language:Chinese
-
Abstract:
Acne vulgaris is an inflammatory disease of hair follicle sebaceous gland units,with an incidence of up to 85% in adolescents.The pathogenesis is closely related to androgen,sebum secretion,lipophilic microbial infection,and immune-inflammatory reaction.This article reviews the signaling pathways related to acne from the aspects of inflammatory signaling pathways and sebum secretion pathways.