Effect of Coix-seed Reactive Derivatives(CRD) on Cold Sensitivity of Female Hands and Feet: A Randomized Controlled Trial

VernacularTitle:Coix-seed Reactive Derivatives(CRD)の女性における手足の冷えに与える影響: 無作為化比較対照試験
Author: Nobutaka SUZUKI ¹ ; Hoko KYO ¹ ; Hirotaka OKUWA-HAYASHI ² ; Kazuo UEBABA ³ ; Shintaro HASHIMOTO ²
Author Information

1. Department of Complementary and Alternative Medicine Clinical Research and Development, Kanazawa University Graduate School of Medical Science
2. Urata Clinic, Hospy Medical Association
3. Faculty of Food Culture, Kurashiki Sakuyo University
Keywords: Coix lacryma-jobi L. var. ma-yuen Stapf; Coix-seed Reactive Derivatives (CRD); Cold sensitivity; randomized controlled trial (RCT)
From:Japanese Journal of Complementary and Alternative Medicine 2020;17(1):33-36
CountryJapan
Language:Japanese
Abstract: We evaluated the effect of Coix-seed Reactive Derivatives (CRD) on cold sensitivity of female hands and feet. Ninety females were assigned randomly to 3 groups and CRD(2g/day, 4g/day or placebo) was administrated for 8weeks. Significant improvement of cold sensitivity was observed in both the 2g/day and 4g/day groups. It was speculated that a naringenin and a quercetin as active ingredients of adlay hull may play a critical role in ameliorating effect on blood flow.