Nasal Continuous Positive Airway Pressure for Carcinomatous Lymphangitis in End-stage Malignant Soft Tissue Sarcoma: A Case Report

Natsuko Fukuoka; Akihito Tsuji; Yoshiki Yamagami; Hideki Nishimura; Kosuke Chujo; Akitsu Murakami; Tetsuji Yamamoto

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Nasal Continuous Positive Airway Pressure for Carcinomatous Lymphangitis in End-stage Malignant Soft Tissue Sarcoma: A Case Report

VernacularTitle:軟部肉腫肺転移症例の終末期緩和医療に経鼻的持続陽圧呼吸療法が有用であった1例
Author: Natsuko FUKUOKA ¹ ; Akihito TSUJI ² ; Yoshiki YAMAGAMI ³ ; Hideki NISHIMURA ¹ ; Kosuke CHUJO ¹ ; Akitsu MURAKAMI ² ; Tetsuji YAMAMOTO ²
Author Information

1. Department of Orthopaedic Surgery, Kagawa University
2. Faculty of Medicine Department of Palliative Care Center, Kagawa University
3. Faculty of Medicine Department of Clinical Oncology, Kagawa University
Keywords: soft tissue sarcoma; nasal continuous positive airway pressure (nasal CPAP); carcinomatous lymphangitis; palliative care
From:Palliative Care Research 2020;15(3):233-237
CountryJapan
Language:Japanese
Abstract: Background: In the end stage of malignant bone and soft tissue tumors with lung metastasis, it is often necessary to relieve symptoms of dyspnea due to tumor enlargement and carcinomatous lymphangitis. We report a case in which nasal continuous positive airway pressure (nasal CPAP) was effective as a palliative treatment. Case: A 66-year-old male underwent wide resection with a diagnosis soft tissue sarcoma of right femur. Four years after surgery, he was hospitalized for hilar lymph node metastasis, multiple bone metastases, and carcinomatous lymphangitis. He was treated with nasal CPAP for dyspnea, and communication was possible until the day before his death. Discussion: For end-stage respiratory symptoms, medication therapy such as morphine or steroids is often used for palliation, but often symptoms are not sufficiently improved. Nasal CPAP might be a useful treatment for palliation for rapidly progressing respiratory failure.