A Case of Giant Mobile Left Atrial Thrombus during Dabigatran Therapy
- VernacularTitle:ダビガトラン投与下に巨大左房内遊離血栓を認めた1例
- Author:
Shun SATO
1
;
Takeshi NISHINA
1
;
Masashi YADA
1
;
Yuichi UEDA
1
;
Kazuo YAMANAKA
1
Author Information
- Keywords: left atrial thrombus; non valvular atrial fibrillation; dabigatran; DOAC
- From:Japanese Journal of Cardiovascular Surgery 2020;49(4):205-209
- CountryJapan
- Language:Japanese
- Abstract: Dabigatran is a new/direct oral anticoagulant drug unlike warfarin. It is being increasingly used to prevent thromboembolism in patients with nonvalvular atrial fibrillation. We present the case of a 77-year-old woman with a giant left atrial thrombus in spite of anticoagulation therapy with dabigatran 300 mg/day. She had developed a cerebral infarction 18 months previously and was switched from warfarin to dabigatran. However, magnetic resonance imaging showed multiple new cerebral infarcts, and computed tomography scan and echocardiogram revealed a giant thrombus measuring 37×29 mm in the left atrium. Thrombectomy and left atrial appendage closure were urgently performed. Dabigatran was changed to warfarin again after the operation. She has had no recurrent thromboembolic event since then.
