Analysis on application of regulatory dendritic cell in renal transplantation
10.3969/j.issn.1674-7445.2020.05.016
- VernacularTitle:调节性树突状细胞在肾移植中的应用分析
- Author:
Haiyan XU
1
;
Renfang XU
;
Xiaozhou HE
Author Information
1. Department of Urology, the Third Affiliated Hospital of Soochow University, the First People's Hospital of Changzhou, Changzhou 213003, China
- Publication Type:Research Article
- Keywords:
Regulatory dendritic cell;
Renal transplantation;
Cell therapy;
Immunosuppressant;
Immune tolerance;
Immune response;
Immune regulation;
Rejection
- From:
Organ Transplantation
2020;11(5):622-
- CountryChina
- Language:Chinese
-
Abstract:
How to reduce the use of immunosuppressant is one of the difficult problems to be solved in the field of organ transplantation. Cell therapy is considered as an effective solution to replace immunosuppressant with a promising clinical application. Regulatory dendritic cell (DCreg) has attracted widespread attention due to its ability to induce immune tolerance. Kidney is a solid and non-immune organ. Whether the particularity of body and the local microenvironment of recipients after renal transplantation affects the application of DCreg is the focus of research. In this article, the application of DCreg in renal transplantation was analyzed from the perspective of renal immunity.
