Application value of quantitative parameters of contrast-enhanced ultrasound in evaluating donor liver from donation after brain death
10.3969/j.issn.1674-7445.2020.05.014
- VernacularTitle:超声造影定量参数在评估脑死亡器官捐献供肝中的应用价值
- Author:
Xiuyun REN
1
;
Nong GAO
;
Yipeng PAN
;
Faqin LYU
;
Wei LI
Author Information
1. Department of Ultrasonography, the Third Medical Center of Chinese PLA General Hospital, Beijing 100039, China
- Publication Type:Research Article
- Keywords:
Donation after brain death;
Contrast-enhanced ultrasound;
Micro-perfusion;
Area under curve;
Maximum intensity;
Time-to-peak;
Mean transit time
- From:
Organ Transplantation
2020;11(5):610-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the application value of quantitative parameters of contrast-enhanced ultrasound (CEUS) in evaluating the donor liver from donation after brain death (DBD). Methods Clinical data of 25 DBD donor livers and 10 healthy adult livers were retrospectively analyzed. CEUS examinations of DBD donor livers and healthy livers were collected. Quantitative parameters included the area under curve (AUC), maximum intensity (Imax), time to peak (TTP) and mean transit time (mTT), etc. Results Among 25 cases of DBD donor livers, 23 cases showed normal enhancement pattern, and the other 2 cases presented with abnormal enhancement pattern. Compared with the control group, the AUC, Imax and mTT values of DBD donor livers were significantly decreased (all P < 0.05). Conclusions CEUS quantitative parameters can be effective means to evaluate the micro-perfusion of DBD donor livers.
