Diastolic dysfunction grading, echocardiographic and electrocardiogram findings in 50 patients with apical hypertrophic cardiomyopathy
- Author:
Aslannif Roslan
1
;
Suraya Hani Kamsani
1
;
Hui Beng Koh
1
;
Yee Sin Tey
1
;
Kin Leong Tan
1
;
Chan Ho Tham
1
;
Mohd Saad Jalaluddin
1
;
Mohamed Nazrul Mohamed Nazeeb
1
;
Nay Thu Win
1
;
Ahmad Tantawi Jauhari Aktifanus
1
;
Malini Kerisnan
1
;
Wan Nabeelah
1
;
Muhd Najmi Hakim Abdul Rani
2
;
Ai Ming Tan
2
;
Amin Ariff Nuruddin
1
Author Information
- Publication Type:Journal Article
- Keywords: Apical; Hypertrophic cardiomyopathy; Echocardiogram; Electrocardiogram; Diastolic dysfunction; Malaysia
- From: The Medical Journal of Malaysia 2019;74(6):521-526
- CountryMalaysia
- Language:English
- Abstract: Introduction: Apical Hypertrophic Cardiomyopathy (Apical HCM) is an uncommon variant of hypertrophic cardiomyopathy, but it is relatively more common in Asian countries. This is a retrospective, non-randomised, single centre study of patients with Apical HCM focusing on their diastolic dysfunction grading, echocardiographic parameters and electrocardiograms (ECG). Methods: All Apical HCM patients coming for clinic visits at the Institut Jantung Negara from September 2017 to September 2018 were included. We assessed their echocardiography images, grade their diastolic function and reviewed their ECG on presentation. Results: Fifty patient were included, 82% (n=41) were males and 18% (n=9) females. The diastolic function grading of 37 (74%) patients were able to be determined using the updated 2016 American Society of Echocardiography (ASE) diastolic guidelines. Fifty percent (n=25) had the typical ace-ofspades shape left ventricle (LV) appearance in diastole and 12% (n=6) had apical pouch. All patients had T inversion in the anterior leads of their ECG, and only 52% (n=26) fulfilled the ECG left ventricular hypertrophy (LVH) criteria. Majority of our patients presented with symptoms of chest pain (52%, n=26) and dyspnoea (42%, n=21). Conclusion: The updated 2016 ASE guideline makes it easier to evaluate LV diastolic function in most patients with Apical HCM. It also helps in elucidating the aetiology of dyspnoea, based on left atrial pressure. Clinicians should have a high index of suspicion for Apical HCM when faced with deep T inversion on ECG, in addition to a thick LV apex with an aceof-spades appearance during diastole.
