Genetic counseling and precise diagnosis and treatment strategies for lung cancer
DOI：10.3872/j.issn.1007-385x.2020.08.001
- VernacularTitle:肺癌的遗传咨询与精准诊疗策略
- Author:
BAI Rilan
1
;
LIU Yining
1
;
CUI Jiuwei
1
Author Information
1. (Cancer Center, the First Hospital of Jilin University, Changchun 130021, Jilin, China
- Publication Type:Journal Article
- Keywords:
lung neoplasms;
genetic susceptibility;
single nucleotide polymorphism;
genetic counseling;
precision medicine
- From:
Chinese Journal of Cancer Biotherapy
2020;27(8):835-842
- CountryChina
- Language:Chinese
-
Abstract:
Environmental factors are important risk factor for lung cancer. Smokers are 20 times more likely to develop lung cancer than non-smokers. However, less than 20% of smokers develop lung cancer. In recent years, many studies have shown genetic polymor‐phism plays an important role in the development of lung cancer, mainly involving single nucleotide polymorphisms and rare highexogenous mutations. The in-depth research of the gene polymorphism will be beneficial to the screen of susceptible genes in lung cancer and genetically high-risk population, providing genetic counseling and evidence for clinically precise diagnosis and treatment. This article mainly summarizes the contents regarding genetic susceptibility of lung cancer and high-risk population screening, early diagnosis of lung cancer as well as precise medication of advanced lung cancer.
- Full text:20200801.pdf
