Clinical features and pathogenesis of liver injury caused by SARS, MERS and COVID-19
10.3969/j.issn.1001-5256.2020.08.046
- VernacularTitle:SARS、MERS和COVID-19感染所致肝损伤的临床特征及机制
- Author:
Hang GONG
1
;
Zhong HUANG
1
;
Xianli LIU
2
Author Information
1. Department of Gastroenterology, The First People’s Hospital of Zigong, Zigong, Sichuan 643000, China
2. Department of Ultrasound, Zigong Hospital of Traditional Chinese Medicine, Zigong, Sichuan 643000, China
- Publication Type:Research Article
- Keywords:
coronavirus;
liver injury;
peptidyl-dipeptidase A
- From:
Journal of Clinical Hepatology
2020;36(8):1887-1890
- CountryChina
- Language:Chinese
-
Abstract:
Coronavirus disease 2019 caused by severe acute respiratory syndrome coronavirus 2 has become a serious threat to global public health security. Besides lung diseases, severe cases are also accompanied by varying degrees of liver injury. Previous studies have shown that patients infected with severe acute respiratory syndrome coronavirus and Middle East respiratory syndrome coronavirus may also suffer from liver injury, which is closely associated with disease severity. This article elaborates on the clinical features and pathogenesis of liver injury caused by these three types of highly pathogenic human coronavirus, in order to help clinicians better understand this disease and make accurate decisions.