Analysis of Drug Therapy for a Case of Child with Human Herpesvirus 7 Infection in Central Nervous System by Clinical Pharmacist
- VernacularTitle:临床药师对1例中枢神经系统人类疱疹病毒7型感染患儿的用药分析
- Author:
Mengjiao SONG
1
;
Limin WANG
2
;
Bin ZHANG
2
;
Jinhai DUAN
2
,
3
;
Xiaojuan ZHANG
4
Author Information
1. Dept. of Pharmacy，Zhuhai People’s Hospital/Zhuhai Hospital Affiliated with Jinan University，Guangdong Zhuhai 519000，China
2. Dept. of Neurology，Guangdong Provincial People’s Hospital/Guangdong Academy of Medical Sciences/ Guangdong Institute of Neurosciences，Guangzhou 510080，China
3. The Second School of Clinical Medicine，Southern Medical University，Guangzhou 510515，China
4. Dept. of Pharmacy，Guangdong Provincial People’s Hospital/Guangdong Academy of Medical Sciences，Guangzhou 510080，China
- Publication Type:Journal Article
- Keywords:
Clinical pharmacist;
Central nervous system infection;
Human herpesvirus 7;
Drug therapy;
Medication analysis
- From:
China Pharmacy
2020;31(16):2029-2033
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE：To investigate the r ole of clinical pharmacists on the therapy for human herpesvirus 7（HHV-7） infection in central nervous system. METHODS ：The clinical pharmacists participated in the treatment process of the hospitalized patient who was a 15-year-old patient with central nervous system infection. The doctor initially gave Levetiracetam tablets （500 mg，bid，po）to control epilepsy symptoms ，and Acyclovir for injection （500 mg，q8 h，ivgtt）for antiviral treatment. According to the large red wheal scattered rubella on the limbs and back of the patient ，clinical pharmacists recommended to give Dexamethasone sodium phosphate injection （10 mg，qd，iv）and Loratadine tablets （10 mg，qd，po）for anti-allergy treatment ；in view of involuntary shaking of limbs in the patient ，clinical pharmacists recommended to continue to give Dexamethasone sodium phosphate injection intravenously to control inflammation and Xingnaojing injection （20 mL，qd，ivgtt） to improve the convulsion. For HHV- 7 infection，based on consulting the relevant guidelines and existing treatment experience ，the clinical pharmacists recommended discontinuation of acyclovir ， dexamethasone combined with Human immunoglobulin （pH 0278）（17.5 g，qd，ivgtt）for impact therapy should be used and adverse drug reactions and therapeutic effects should be monitored at the same time. RESULTS ： The physiciansaccepted the suggestions of clinical pharmacists. The patient was improved and discharged from the hospital after 18 days of treatment. CONCLUSIONS ： During the treatment of ineffective case of clinic rare central nervous system infectious diseases with routine a ntiviral drugs ，clinical pharmacists assisted physicians to improve their treatment plan and ensure the effectiveness and safety of patient ’s medication.
