Prognostic factors of survival for patients with duodenal papilla carcinoma after pancreaticoduodenectomy
10.3760/cma.j.issn.1007-631X.2019.12.002
- VernacularTitle:十二指肠乳头癌行胰十二指肠切除术患者预后相关因素分析
- Author:
Xueliang FU
1
;
Jianyu YANG
;
Dejun LIU
;
Yanmiao HUO
;
Wei LIU
;
Junfeng ZHANG
;
Rong HUA
;
Yongwei SUN
Author Information
1. 上海交通大学医学院附属仁济医院胆胰外科 200127
- Keywords:
Duodenal neoplasms;
Pancreaticoduodenectomy;
Prognosis
- From:
Chinese Journal of General Surgery
2019;34(12):1021-1025
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prognostic factors of survival for patients with duodenal papilla carcinoma (DPC) after pancreaticoduodenectomy.Methods 98 DPC patients undergoing pancreaticoduodenectomy with follow-up from Jan 2010 to Dec 2017 at Renji Hospital,School of Medicine,Shanghai Jiao Tong University were analyzed retrospectively.Results 80 Cases were followed up.The 1,3,and 5 year survival rates of 80 patients were 89.9%,72.4%,and 66.6%,respectively.Univariate analysis showed tumor size,T stage,N stage,TNM stage,tissue differentiation degree were related to postoperative survival(all P <0.05).Multivariate analysis showed that tumor size,N stage,TNM stage,and tissue differentiation degree were independent factors influencing postoperative prognosis(all P < 0.05).Conclusions Tumor size,N stage,TNM stage and tumor tissue differentiation degree were independent factors influencing the prognosis of DPC after pancreaticoduodenectomy,suggesting that early diagnosis,early treatment and radical resection were the key to improve the postoperative prognosis of DPC.