Relationship between modified Frailty Index and development of delirium after artificial joint re-placement in elderly patients
10.3760∕cma.j.issn.0254-1416.2019.10.003
- VernacularTitle:修正衰弱指数与人工关节置换术后老年病人谵妄发生的关系
- Author:
Fan CUI
1
;
Wei ZHAO
;
Chunjing LI
;
Dongliang MU
Author Information
1. 北京大学第一医院麻醉与重症医学科 100034
- Keywords:
Arthroplasty,replacement;
Aged;
Delirium;
Modified frailty index
- From:
Chinese Journal of Anesthesiology
2019;39(10):1158-1161
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the relationship between modified Frailty Index(mFI)and de-velopment of delirium after artificial joint replacement in elderly patients.Methods Elderly patients(aged≥60 yr)who scheduled for elective hip or knee replacement,were enrolled.Preoperative frailty was assessed using the mFI scale.All the patients received surgery under combined spinal-epidural anesthesia.Primary outcome was the incidence of delirium within 5 days after operation,and delirium was assessed by Confusion Assessment Method or Confusion Assessment Method-Intensive Care Unit.The patients were di-vided into delirium group and non-delirium group according to whether delirium occurred or not.Results A total of 620 patients were included in the study,the mFI was 0.09(0.18),and the incidence of delirium within 5 days after surgery was 8.5％.The results of multivariate logistic regression analyses showed that in-crease in age(OR 1.068,95％CI 1.018-1.120,P＝0.007),higher postoperative consumption of mor-phine(OR 1.089,95％CI 1.051-1.128,P＜0.01)and higher mFI(OR 2.465,95％CI 1.636-3.714,P＜0.01)were the independent risk factors for postoperative delirium.Conclusion Higher mFI is the independent risk factor for delirium after artificial joint replacement in elderly patients.
