Advances on researches of clinical pathology and pathogenesis in patients with acute alcoholic hepatitis
10.3969/j.issn.1008-9691.2019.05.032
- VernacularTitle:酒精性肝炎的临床病理及发病机制研究进展
- Author:
Wenjuan CAI
1
;
Zhenglu WANG
Author Information
1. 天津市第一中心医院病理科
- Keywords:
Alcoholic hepatitis;
Pathogenesis;
Pathological characteristics;
Prognosis assessment
- From:
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
2019;26(5):635-637
- CountryChina
- Language:Chinese
-
Abstract:
Alcoholic hepatitis (AH) is an acute severe decompensated alcoholic liver disease (ALD), commonly occurring in heavy drinkers. The pathogenesis of AH is still not fully understood, which may be related to the interactions of multiple complex factors such as alcohol metabolism, inflammation and heredity, etc. Under the background of continuous alcoholic exposure, the pathological changes include hepatocyte steatosis, liver inflammation and fibrosis occurring in the body. This paper summarizes the recent research literatures related to the clinicopathological features, pathogenesis and prognosis evaluation of ALD to comprehensively understand the pathogenesis and pathophysiological characteristics of AH in order to provide theoretical basis for clinical diagnosis and treatment of this disease.
