A Case of Invasive Aspergillosis in Transplanted Kidney and Perirenal Area.
- Author:
Hyun Hee NA
1
;
Seong Woo HONG
;
Mun Cheol KIM
;
Yun Kyung KANG
;
Young Chul YOON
;
Haeng Il KOH
Author Information
1. Department of Internal Medicine, Seoul Paik Hospital, Seoul, Korea. puppledoc@naver.com
- Publication Type:Case Report
- Keywords:
Aspergillus;
Invasive aspersillosis;
Kidney transplantation
- MeSH:
Anti-Bacterial Agents;
Antifungal Agents;
Aspergillosis;
Aspergillus;
Azotemia;
Biopsy;
Fever;
Hematuria;
Humans;
Immunosuppressive Agents;
Incidence;
Kidney;
Kidney Transplantation;
Male;
Pancytopenia;
Percussion;
Transplants
- From:The Journal of the Korean Society for Transplantation
2008;22(1):135-137
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Recently, the incidence of fungal infection increases because of immunosuppressive therapy and chemotherapy. In immunosuppressed transplant recipients, Aspergillus can be a dangerous pathogen, capable of inducing fulminant clinical disease. Invasive fungal infections are life-threatening complications in solid-organ transplantation. Although the rate of fungal infections in transplant recipients is lower than that of other infections, the mortality rate is higher. A 34 year-old male was admitted to our hospital with fever and gross hematuria. He had received renal transplantation 2 years ago and had been transferred the other hospital 1 month ago. Initial laboratory data evaluation showed a pancytopenia and azotemia. We thought that pancytopenia was caused by immunosuppressive agents and infection. The patient was treated with antibiotics but fever was not subsided. After 4 days, he complained of transplant site pain and tenderness to percussion. A percutaneous renal biopsy was performed. Microscopic examination showed invasive aspergillosis in transplanted kidney and perirenal area. We removed the transplanted kidney and perirenal tissue, and prescribed antifungal agents for 3 months.
