Molecular immune pathogenesis and diagnosis of COVID-19
- Author:
Xiaowei LI
1
;
Manman GENG
;
Yizhao PENG
;
Liesu MENG
;
Shemin LU
Author Information
1. Department of Biochemistry and Molecular Biology
- Keywords:
Coronavirus;
SARS-CoV-2;
SARS-CoV;
MERS-CoV;
Pathogenesis
- From:
Journal of Pharmaceutical Analysis
2020;10(2):102-108
- CountryChina
- Language:Chinese
-
Abstract:
Coronavirus disease 2019 (COVID-19) is a kind of viral pneumonia which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The emergence of SARS-CoV-2 has been marked as the third introduction of a highly pathogenic coronavirus into the human population after the severe acute respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory syndrome coro-navirus (MERS-CoV) in the twenty-first century. In this minireview, we provide a brief introduction of the general features of SARS-CoV-2 and discuss current knowledge of molecular immune pathogenesis, diagnosis and treatment of COVID-19 on the base of the present understanding of SARS-CoV and MERS-CoV infections, which may be helpful in offering novel insights and potential therapeutic targets for combating the SARS-CoV-2 infection.
