Ocular surface change of primary pterygium with OCULUS keratograph
10.3760/cma.j.issn.2095-0160.2018.12.009
- VernacularTitle:应用眼表分析仪研究原发性翼状胬肉患者眼表变化
- Author:
Zhongting LI
1
,
2
,
3
;
Xuan LENG
;
Yanli ZHANG
;
Tingxin HU
;
Qi ZHAO
;
Minbin YU
Author Information
1. 510060 中山大学中山眼科中心眼科学国家重点实验室
2. 中山大学中山眼科中心
3. 528400 中山市人民医院 眼科医疗中心
- Keywords:
Pterygium;
OCULUS Keratograph;
Break up time of tear film
- From:
Chinese Journal of Experimental Ophthalmology
2019;36(12):942-945
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the correlation between pterygium area and the clinical manifestation and signs of primary pterygium obtained from OCULUS Keratograph.Methods A prospective case observation study was performed.Thirty-nine (55 eyes) primary pterygium patients were selected from June to September 2016 in Zhongshan People's Hospital.The area of the pterygium invaded cornea and duration of pterygium were recorded.The ocular surface condition was detected by corneal fluorescein staining.The break up time of tear film (BUT) and the gland function score were measured with OCULUS Keratograph.This study was approved by the Ethics Committee of Zhongshan People's Hospital (2015 [13]).All operations followed the Helsinki Declaration and all patients signed informed consent forms.Results The areas of pterygium invaded cornea was 2-20 mm2,the mean size was 5 (3,10) mm2;the duration of pterygium was 3-8 years,the mean duration was 5 (4,6)years;the BUT was 2.1-15.0 seconds,the mean BUT was (6.3±3.0) seconds.The mean gland function score was 2 (1,3).The area of pterygium was not significantly correlated with the duration of pteryguim (r =0.197,P =0.148),while it was negatively correlated with BUT (r=-0.711,P<0.001) and positively correlated with the tarsal gland score (r =0.554,P<0.001).What's more,82% (45/55 eyes) of the patients' tear film rupture appeared firstly near pterygium's head.Conclusion OCULUS Keratograph can directly evaluate the ocular surface condition of pterygium patients in a non-contact and non-invasive method.Assessing the ocular surface damage by observing the area of pterygium invaded cornea may provide a prospective treatment for pterygium patients.