5-Aminolevulinic Acid Fluorescence Discriminates the Histological Grade of Extraventricular Neurocytoma.
10.14791/btrt.2013.1.1.45
- Author:
Sang Woo SONG
1
;
Young Hoon KIM
;
Sung Hye PARK
;
Chul Kee PARK
Author Information
1. Department of Neurosurgery, Konkuk University Hospital, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Extraventricular neurocytoma;
Fluorescence guided surgery;
5-aminolevulinic acid
- MeSH:
Brain Neoplasms;
Fluorescence*;
Neurocytoma*
- From:Brain Tumor Research and Treatment
2013;1(1):45-49
- CountryRepublic of Korea
- Language:English
-
Abstract:
Extraventricular neurocytomas are rare brain tumors that have a diverse range of clinical characteristics. We describe two cases involving fluorescence-guided resection of extraventricular neurocytoma using 5-aminolevulinic acid (5-ALA) and evaluate the efficacy of the technique. We found that the tumor reactions to 5-ALA differed depending on the histologic grade. This finding shows that the 5-ALA fluorescence reaction may potentially be used as a biomarker of the clinical behavior of these tumors. To our knowledge, this is the first report in which fluorescence-guided resection was utilized for the resection of extraventricular neurocytomas.
