Chronic thromboembolic pulmonary hypertension: Outcomes of surgical effect in patients with unilateral main pulmonary artery occlusion
- VernacularTitle:慢性血栓栓塞性肺动脉高压：单侧肺动脉主干闭塞患者的外科治疗
- Author:
Wu SONG
1
;
Zhaoji ZHONG
1
;
Shanshan ZHENG
1
;
Yunhu SONG
1
;
Sheng LIU
1
Author Information
1. Department of Cardiac Surgery, Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing, 100037, P.R.China
- Publication Type:Journal Article
- Keywords:
Pulmonary hypertension;
thromboembolism;
unilateral occlusion;
endarterectomy;
surgical treatment
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2020;27(07):813-818
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize the clinical characteristics and the long-term results of pulmonary thromboendarterectomy (PTE) in the chronic thromboembolic pulmonary hypertension (CTEPH) patients with unilateral main pulmonary artery occlusion. Methods We retrospectively analyzed the clinical data of 15 CTEPH patients with unilateral main pulmonary artery occlusion in Fuwai Hospital between 2004 and 2018. There were 11 males and 4 females aged 34.1±12.0 years at operation. Results The mean circulatory arrest was 31.1±12.1 minutes. The ICU stay was 5 (2-29) d. The hospital stay was 15 (8-29) d. There was no hospital death. There was a decline in systolic pulmonary artery pressures (sPAP, 69.9±27.9 mm Hg to 35.1±9.7 mm Hg, P=0.020) after surgery. On postoperative V/Q scan, only 6 patients (40.0%) had significant improvement in reperfusion (≥75% estimated) of the occluded lung. There was no death during the median observation period of 49 months follow-up, while 2 patients had recurrence of pulmonary embolism. Conclusion CTEPH patients with unilateral main pulmonary artery occlusion represent a challenging cohort. PTE is a curative resolution in both early- and long- term results, although there is a high requirement of perioperative management and a high risk of postoperative complications and rethrombosis.
