Surgical treatment for hypertrophic obstructive cardiomyopathy with moderate-to-severe mitral regurgitation through right mini-thoracotomy
- VernacularTitle:右胸微创手术治疗肥厚型梗阻性心肌病合并中度以上二尖瓣反流
- Author:
Zhaolei JIANG
1
;
Ju MEI
1
;
Min TANG
1
;
Hao LIU
1
;
Nan MA
1
;
Sai’e SHEN
2
;
Fangbao DING
1
;
Jianbing HUANG
1
Author Information
1. Department of Cardiothoracic Surgery, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200092, P.R.China
2. Department of Anesthesiology, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200092, P.R.China
- Publication Type:Journal Article
- Keywords:
Hypertrophic obstructive cardiomyopathy;
mitral regurgitation;
systolic anterior motion;
edge-to-edge
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2020;27(07):754-757
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect and safety of surgical treatment for hypertrophic obstructive cardiomyopathy (HOCM) with mitral regurgitation (MR) through right mini-thoracotomy. Methods From January 2008 to June 2018, 54 patients with HOCM and moderate-to-severe MR underwent modified Morrow procedure and edge-to-edge mitral valvuloplasty through right mini-thoracotomy, including 31 males and 23 females, with an average age of 47.1±12.6 years. All patients had systolic anterior motion (SAM) phenomenon. Preoperative left ventricular outflow tract pressure gradient (LVOTPG) was 93.6±32.8 mm Hg, interventricular septum thickness (IVST) was 24.8±2.8 mm. Results Surgeries in all patients were completed successfully. No early death or interventricular septal perforation occurred. One (1.9%) patient received permanent pacemaker implantation due to the complete atrial-ventricular block. At discharge, postoperative LVOTPG (18.1±6.2 mm Hg) and IVST (14.5±2.1 mm) were significantly decreased compared with the preoperative values (P<0.05). No MR or SAM was observed in all patients. The follow-up time was 6-132 months, and during this period, no death, MR or SAM occurred. The average LVOTPG was 19.4±5.7 mm Hg, and the average IVST was 14.2±1.5 mm. Conclusion Morrow procedure and edge-to-edge mitral valvuloplasty through right mini-thoracotomy is a safe and effective method for treatment of HOCM with moderate-to-severe MR.
