- Author:
LIU Jie
1
;
TANG Hua
2
Author Information
- Publication Type:Review
- Keywords: Bisphosphonates; Osteonecrosis; Rat model; Osteoporosis; Bone malignancy
- From: Journal of Prevention and Treatment for Stomatological Diseases 2017;25(2):133-136
- CountryChina
- Language:Chinese
- Abstract: With the wide use of bisphosphonates in bone diseases such as osteoporosis and bone metastases of malignant tumors, bisphosphonate-related osteonecrosis of the jaw has gained widely attention as a severe side effect. Animal model is a useful way to study bisphosphonate-related osteonecrosis of the jaw, among which rat model is used most usually. This article reviewed the establishment of rat model of bisphosphonate-related osteonecrosis of the jaw and relevant examinations.
- Full text:大鼠双膦酸盐相关性颌骨坏死模型的建立.pdf