Research advances on the chemical constituents and pharmacological effects of snow lotus
10.16438/j.0513-4870.2020-0445
- VernacularTitle:雪莲的化学成分及药理作用研究进展
- Author:
Lu-ming YANG
1
;
Hu-biao CHEN
2
;
Qiao-ru GUO
1
;
Wen-min ZHOU
1
;
Pei-min HUANG
1
;
Zeng-bao WU
3
;
Jian-ye ZHANG
1
Author Information
1. Guangdong Provincial Key Laboratory of Molecular Target and Clinical Pharmacology, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou 511436, China
2. School of Chinese Medicine, Hong Kong Baptist University, Hong Kong, China
3. Key Laboratory of Xinjiang Phytomedicine Resources of Ministry of Education, School of Pharmacy, Shihezi University, Shihezi 832000, China
- Publication Type:Research Article
- Keywords:
snow lotus;
flavonoid;
lignan;
anti-tumor, anti-inflammation
- From:
Acta Pharmaceutica Sinica
2020;55(7):1466-1477
- CountryChina
- Language:Chinese
-
Abstract:
Snow lotus is a medicinal plant with a wide range of pharmacological activities. It has been used to treat rheumatoid arthritis, cough with cold, stomach ache, dysmenorrhea, and altitude sickness in traditional medicine. This review summarizes the bioactive components in six species of snow lotus including flavonoids, lignans, phenolic compounds, phenylpropanoids, and sesquiterpenes present in Saussurea involucrate (SI), Saussurea obvallata (SO), Saussurea laniceps (SL), Saussurea medusa (SM), Saussurea stella (SS) and Saussurea tridactyla (ST). We review the pharmacological and related molecular mechanisms by which these components exert antineoplastic, anti-inflammatory, and antioxidant effects and promote lipid catabolism, and provide a reference for the future study of the traditional Chinese medicinal chemistry and pharmacological activities of snow lotus.
