High seroprevalence of anti-Fasciola antibody among cattle farm workers and dwellers in Kelantan
- Author:
Najib, M.A.
1
;
Noor-Izani, N.J.
1
;
Wan-Nor-Amilah, W.A.W.
1
;
Wong, W.K.
1
;
Faez, A.M.
2
Author Information
- Publication Type:Journal Article
- From:Tropical Biomedicine 2020;37(No.2):389-396
- CountryMalaysia
- Language:English
- Abstract: Human fascioliasis is a public health problem particularly in areas where ruminants are raised. The aims of this study were to determine the seroprevalence of anti-Fasciola antibody and the associated risk factors among cattle farm workers and dwellers in Kelantan. A total of 90 blood samples were collected in this cross-sectional study. A set of validated questionnaire was used to obtain information on socio-demographic profiles and dietary habits of participants. The sera were subjected to enzyme linked immunosorbent assay (ELISA) for the detection of anti-Fasciola IgG antibody. The association between seropositivity and the significant risk factors were determined via logistic regression. From the result, serological screening revealed 60 (67%) participants positive for anti-Fasciola IgG antibody. The factors found to be significantly associated with seropositivity against anti-Fasciola IgG antibody were the age group of 18 years old and above with calculated odds ratio of 3.2 times (p=0.032) and the duration of farming activities of more than 5 years with calculated odds ratio of 2.6 times (p=0.036). In conclusion, Fasciola infection is prevalent among cattle farm workers and dwellers in Kelantan.
- Full text:8.2020my1128.pdf
