Research progress of sonodynamic therapy in the field of stomatology
10.12016/j.issn.2096-1456.2020.08.011
- Author:
XU Bin
1
;
BI Liangjia
1
Author Information
1. Department of Stomatology, the Fourth Affiliated Hospital of Harbin Medical University
- Publication Type:Review
- Keywords:
sonodynamic therapy;
ultrasound;
sonosensitizer;
singlet oxygen theory;
cavitation effects;
apoptosis;
periodontitis;
oral tumor;
oral mucosal disease;
nanoparticles
- From:
Journal of Prevention and Treatment for Stomatological Diseases
2020;28(8):535-539
- CountryChina
- Language:Chinese
-
Abstract:
Sonodynamic therapy (SDT) is a cutting-edge method for the biological effects of ultrasound combined with sound-sensitive agents. In recent years, SDT has been a concern of experts and scholars in the oral field, and a series of experimental studies has been carried out. We will introduce the progress of SDT in the field of stomatology from three aspects: the therapeutic mechanism of SDT, the application of SDT in the oral field, and the current situation and future of SDT in the treatment of oral diseases. It is currently believed that singlet oxygen theory, cavitation effects, and induction of apoptosis are the main therapeutic mechanisms. The research of SDT on oral disease prevention mainly focuses on oral tumors (especially squamous cell carcinoma and osteosarcoma) and infectious diseases (such as periodontitis, maxillofacial infection, and oral mucosal disease). Although the current research is still in the experimental stage, with the continuous exploration of sonosensitizers and nanotechnology, SDT will provide great help for the clinical prevention and treatment of oral diseases in the future.
- Full text:声动力疗法在口腔医学领域的研究进展.pdf
