Research progress of drug delivery system based on black phosphorus in tumor diagnosis and treatment
10.11665/j.issn.1000-5048.20200303
- VernacularTitle:基于黑磷的药物递送系统在肿瘤诊疗中的研究进展
- Author:
Huizhen YANG
1
;
Weiwei MU
;
Yongjun LIU
;
Na ZHANG
Author Information
1. 山东大学药学院
- Publication Type:Journal Article
- Keywords:
black phosphorus;
drug delivery;
tumor diagnosis and treatment;
photoacoustic imaging;
photothermal and photodynamic therapy
- From:
Journal of China Pharmaceutical University
2020;51(3):270-276
- CountryChina
- Language:Chinese
-
Abstract:
As a new member of two-dimensional materials, black phosphorus has shown good application prospects in the fields of photoacoustic imaging, photothermal photodynamic therapy, and drug loading due to its excellent characteristics such as good biodegradability, biocompatibility, thickness-dependent tunable direct band-gap, and high surface-to-mass ratio. Because black phosphorus has the characteristics of easy oxidation and degradation, it is coated with relatively stable liposomes or polymeric materials to construct a black phosphorus-based drug delivery system, which shows great potential in tumor treatment and diagnosis and has become a new focus in drug delivery research. In this paper, we introduce the role of black phosphorus in tumor diagnosis and treatment in detail, and summarize the design of black phosphorus-based drug delivery system in recent years as well as its research progress in tumor diagnosis and treatment, in order to provide reference for the research and application of black phosphorus.
