Effect and research progress on continuous hypothermic machine perfusion in preservation of renal graft
10.3969/j.issn.1674-7445.2020.04.017
- VernacularTitle:持续低温机械灌注保存移植肾的作用及其研究进展
- Author:
Fei ZHANG
1
;
Guiyi LIAO
Author Information
1. Department of Urology, the First Affiliated Hospital of Anhui Medical University, Hefei 230000, China
- Publication Type:Research Article
- Keywords:
Renal transplantation;
Hypothermic machine perfusion;
Delayed graft function;
Ischemia-reperfusion injury;
Expanded criteria donor;
LifePort;
Machine perfusion flow;
Resistance index
- From:
Organ Transplantation
2020;11(4):521-
- CountryChina
- Language:Chinese
-
Abstract:
Inevitable ischemia-reperfusion injury (IRI) occurred in organ donation after citizen's death often results in delayed graft function (DGF) after renal transplantation. Although the incidence of DGF had reduced to some extent due to continuous hypothermic machine perfusion (HMP) for renal graft using LifePort, DGF of renal graft remains a major clinical problem. In order to further reduce the incidence of DGF after renal transplantation, renal transplant surgeons should fully understand the role of continuous HMP in renal transplantation, continue to conduct more in-depth basic and applied research. This article mainly summarized the effect of continuous HMP on renal transplantation and its research progress.
