A new treatment strategy for primary liver cancer based on the theory of the oral-gut-liver axis
10.3969/j.issn.1001-5256.2020.07.044
- VernacularTitle:基于口-肠-肝轴理论探讨原发性肝癌的新型治疗策略
- Author:
Cheng ZHOU
1
;
Jiaming ZHANG
;
Li GUO
;
Hailong SI
;
Haijuan XIAO
;
Lin YANG
Author Information
1. The First Clinical Medical College, Shaanxi University of Chinese Medicine, Xianyang, Shaanxi 712000, China
- Publication Type:Research Article
- Keywords:
liver neoplasms;
microbiota;
prebiotics
- From:
Journal of Clinical Hepatology
2020;36(7):1646-1649
- CountryChina
- Language:Chinese
-
Abstract:
Primary liver cancer has various potential causes and insidious onset, and its progression is affected by many factors. Immunotherapy and targeted drug therapy have been used as non-radical treatment methods for primary liver cancer, but they cannot achieve a satisfactory effect and may lead to drug resistance. In recent years, the wide application of 16s high-throughput sequencing and the in-depth studies of microbiology have revealed the key role of microorganisms in the development and progression of liver cancer. The association of the liver with oral and intestinal flora is gradually clarified, and the regulation of oral and intestinal flora has brought new treatment methods for the disease. This article reviews the microbial theory of the oral-gut-liver axis and its application and development in the treatment of primary liver cancer.
