Research advances in hepatocellular carcinoma-related sarcopenia

VernacularTitle:肝细胞癌相关性骨骼肌减少症的研究近况
Author: Suya SHEN ¹ ; Jianzhao HUANG ; Yan LIU ; Jiangwei LIU ; Xuyang ZHANG ; Kunqi YE ; Ningbo PAN
Author Information

1. School of Clinical Medicine, Guizhou Medical University, Guiyang 550000, China
Publication Type:Research Article
Keywords: carcinoma, hepatocellular; skeletal muscle depletion; prognosis
From: Journal of Clinical Hepatology 2020;36(7):1639-1642
CountryChina
Language:Chinese
Abstract: Hepatocellular carcinoma (HCC) is a common malignant tumor and patients with HCC often have liver cirrhosis, with an extremely high 5-year recurrence rate and poor prognosis even after curative treatment. In recent years, sarcopenia has attracted more and more attention as a poor prognostic factor for various malignant tumors; however, there is still a lack of studies on the association between skeletal muscle index and prognosis of HCC in China. Evidence in foreign countries has shown that sarcopenia may be an a negative prognostic factor for HCC patients. This article reviews the etiology and possible pathogenesis of HCC-related sarcopenia and related intervention measures including nutritional supplementation, appropriate physical exercise, and medication, in order to provide a reference for related studies in China.