Effect of modified Blalock-Taussig shunt on the treatment of cyanotic congenital heart diseases in neonates
	    		
		   		
	    	
    	
    	
   		
        
        	
        		- VernacularTitle:改良 Blalock-Taussig 分流术治疗新生儿期紫绀型先天性心脏病的疗效分析
- Author:
	        		
		        		
		        		
			        		Tongkai GE
			        		
			        		
			        		
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			        		;
		        		
		        		
		        		
			        		Jimei CHEN
			        		
			        		
			        		
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			        		Jian ZHUANG
			        		
			        		
			        		
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			        		Jianzheng CEN
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
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			        		Shusheng WEN
			        		
			        		
			        		
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			        		Gang XU
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
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			        		Dandong LUO
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		
		        		
		        		
		        		
    Author Information Author Information
 
			        		
			        		
			        			1. Department of Cardiac Surgery, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academic of Medical Science, Guangzhou, 510080, P.R.China
 
 
- Publication Type:Journal Article
- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Neonates;
			        		
			        		
			        		
				        		modified Blalock-Taussig shunt;
			        		
			        		
			        		
				        		congenital heart disease;
			        		
			        		
			        		
				        		surgery;
			        		
			        		
			        		
				        		treatment
			        		
			        		
	        			
        			
        		
- From:
	            		
	            			Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
	            		
	            		 2020;27(07):737-741
	            	
            	
- CountryChina
- Language:Chinese
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		        	Abstract:
			       	
			       		
				        
				        	Objective    To analyze the effect of modified Blalock-Taussig shunt on the treatment of cyanotic congenital heart diseases in neonates. Methods    The clinical data of 33 neonates undergoing modified Blalock-Taussig shunt between January 1, 2013 and December 31, 2017 were reviewed, including 28 males and 5 females with the age of 3.0-28.0 (18.0±6.1) d and weight of 1.9-3.7 (2.9±0.5) kg. Results    There were 3 (9.1%) in-hospital deaths. Ten (30.3%) patients required early unplanned reoperations after surgery. Five (15.2%) patients were lost to follow-up. In the multivariate analysis, preoperative acidosis, emergency operation and postoperative bedside thoracotomy were independent risk factors of early death. During the follow-up of 18.0-93.0 (40.2±22.5) months, there was no death and 9 (36.0%) survival patients underwent corrective surgery and stage-two palliative surgery. In the multivariate analysis, preoperative hyperhemoglobinemia was an independent risk factor of nonadministration of the corrective surgery and stage-two palliative surgery. Receiver operating characteristic curve showed that preoperative hyperhemoglobinemia was significant in determining whether secondary surgery was possible. Conclusion    The modified Blalock-Taussig shunt is effective in promoting development of pulmonary arteries and preparing for the secondary surgery. The rate of mortality and postoperative complications after the neonatal modified Blalock-Taussig shunt remains high. The rate of secondary surgery is still low during follow-up.