Research progress of microbiota in bronchial asthma
10.16571/j.cnki.1008-8199.2020.07.021
- VernacularTitle: 微生物群在支气管哮喘中的研究进展
- Author:
Ruo-li AN
1
;
Li CHENG
1
;
Qian-ru YUE
1
;
Yi JIANG
2
Author Information
1. The First Clinical Medical College, Shanxi Medical University, Taiyuan 030001,Shanxi,China
2. Department of Respiratory Medicine, The First Hospital of Shanxi Medical University,Taiyuan 030001,Shanxi,China
- Publication Type:Journal Article
- Keywords:
asthma； microbiota； respiratory； intestinal； phenotype； pathogenesis
- From:
Journal of Medical Postgraduates
2020;33(7):781-784
- CountryChina
- Language:Chinese
-
Abstract:
With the development of the new generation of 16S rRNA sequencing technology and metagenomics, the relationship between the microbiota and bronchial asthma (asthma for short) has been increasingly recognized, and has become a research hotspot in the pathogenesis of asthma. It is estimated that more than 10,000 different microbial species inhabit the human body, affecting nutrition, metabolism and immune function of body. The imbalance of microbial flora leads to the disturbance of the internal environment in the body, which causes diseases such as asthma. Asthma is determined by both genetic and environmental effects, and the microbiota plays an important role in the pathogenesis, phenotype and disease severity of asthma. This paper reviews the role of different microbiota in the development of asthma.
