Plexiform Angiomyxoid Myofibroblastic Tumor of the Stomach: A Case Report.
10.3346/jkms.2011.26.11.1508
- Author:
Aeri KIM
1
;
Young Kyung BAE
;
Hyeong Chan SHIN
;
Joon Hyuk CHOI
Author Information
1. Department of Pathology, Yeungnam University College of Medicine, Daegu, Korea. ykbae@ynu.ac.kr
- Publication Type:Case Reports ; Research Support, Non-U.S. Gov't
- Keywords:
Plexiform Angiomyxoid Myofibroblastic Tumor;
Stomach;
Myofibroblast;
Fibromyxoma;
Plexiform
- MeSH:
Dyspepsia/diagnosis;
Endoscopy, Digestive System;
Humans;
Male;
Middle Aged;
Myofibroblasts;
*Myxoma/diagnosis/pathology/surgery;
Pyloric Antrum/pathology;
*Stomach Neoplasms/diagnosis/pathology/surgery
- From:Journal of Korean Medical Science
2011;26(11):1508-1511
- CountryRepublic of Korea
- Language:English
-
Abstract:
Plexiform angiomyxoid myofibroblastic tumor (PAMT) is a recently described mesenchymal tumor of the stomach. We report the first case of PAMT in Korea. A 52-yr-old man underwent esophagogastroduodenoscopy due to dyspepsia for 2 yr. There was a submucosal mass with small mucosal ulceration in the gastric antrum. The tumor measured 3.5 x 2.3 cm in size and showed multinodular plexiform growth pattern of bland-looking spindle cells separated by an abundant myxoid or fibromyxoid matrix rich in small thin-walled blood vessels. The tumor cells were negative for CD117 (c-KIT), CD34 and S-100 protein, but diffusely positive for smooth muscle actin consistent with predominant myofibroblastic differentiation. The patient is doing well without recurrence or metastasis for 5 months after surgery. Although there have been limited follow-up data, PAMT is regarded as a benign gastric neoplasm with histological and immunohistochemical charateristics distinguished from gastrointestinal stromal tumor and other mesenchymal tumors of the stomach.
