Current status of the research on liver injury caused by SARS-CoV-2
10.3969/j.issn.1001-5256.2020.06.047
- VernacularTitle:新型冠状病毒引起肝损伤的研究现状
- Author:
Yaning ZHOU
1
;
Gong FENG
;
Manling LIU
;
Qinqin YAN
;
Liping FAN
;
Man MI
Author Information
1. a. Graduate School
- Publication Type:Research Article
- Keywords:
SARS-CoV-α;
liver injury;
pathologic processes;
therapeutics
- From:
Journal of Clinical Hepatology
2020;36(6):1402-1406
- CountryChina
- Language:Chinese
-
Abstract:
The outbreak of viral pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan, China poses a major threat to public health. SARS-CoV-2 is highly homologous to severe acute respiratory syndrome-associated coronavirus and Middle East respiratory syndrome-associated coronavirus, all of which may cause severe respiratory symptoms. In addition to respiratory symptoms, a considerable proportion of patients with SARS and SARS-CoV-2 infection have varying degrees of liver injury, but their epidemiological features and pathogenesis remains unclear. This article summarizes the epidemiology of SARS-CoV-2 and elaborates on the current status of the research on SARS-CoV-2, possible mechanism of liver injury caused by SARS-CoV-2, and effective treatment regimens, so as to provide a reference and new research ideas for the prevention and treatment of liver injury in patients with SARS-CoV-2 infection.
