Diagnostic and prognostic value of autoantibodies in primary biliary cholangitis
10.3969/j.issn.1001-5256.2020.05.048
- VernacularTitle:自身抗体在原发性胆汁性胆管炎中的诊断及预后价值
- Author:
Futao DANG
1
;
Yingmei TANG
Author Information
1. Department of Gastroenterology, The Second Affiliated Hospital of Kunming Medical University, Kunming 650000, China
- Publication Type:Research Article
- Keywords:
cholangitis, sclerosing;
autoantibodies;
diagnosis;
prognosis
- From:
Journal of Clinical Hepatology
2020;36(5):1164-1166
- CountryChina
- Language:Chinese
-
Abstract:
Primary biliary cholangitis (PBC) is an autoimmune cholestatic liver disease with unknown etiology. Liver biopsy is an important diagnostic tool, but its clinical application is limited due to its invasiveness. Autoantibodies have special diagnostic and prognostic value for PBC, especially anti-mitochondrial antibodies and antinuclear antibodies, and each antibody has unique clinical significance. This article reviews the diagnostic and prognostic significance of autoantibodies associated with PBC and related research advances.
