A Case of Perioperative Management in a Patient with Rare Red Blood Cell Phenotype
- Author:
Nurulhuda Abd Kadir1,2, Siti Salmah Noordin2,3, Mohd Hilmi Senin1,2, Maryam Jameelah Aizuddin1,2, Mohd. Ismail Armawai1, Nor Hafizah Ahmad1
1
Author Information
1. 1 National Blood Centre, Jalan Tun Razak, 50400 Kuala Lumpur, Malaysia 2 Regenerative Medicine Cluster, Advanced Medical and Dental Institute, Universiti Sains Malaysia, 13200 Bertam, Kepala Batas, Pulau Pinang, Malaysia 3 Transfusion Medicine Unit, Advanced Diagnostic Laboratory, Advanced Medical and Dental Institute, Universiti Sains Malaysia, 13200 Bertam, Kepala Batas, Pulau Pinang, Malaysia
- Publication Type:Journal Article
- Keywords:
Patient blood management;
Transfusion;
Phenotype;
Red blood cells
- From:Malaysian Journal of Medicine and Health Sciences
2019;15(SUPPLEMENT 9):198-200
- CountryMalaysia
- Language:English
-
Abstract:
The current focus of perioperative management of anaemia has shifted from allogeneic transfusion to optimising and conserving the patient’s blood through the implementation of patient blood management (PBM) strategies. We hereby report a case to illustrate the success of applying PBM strategies in managing a surgical patient with an extremely rare red blood cells (RBC) phenotype. An 80-year-old Malay man was planned for urgent major abdominal surgery following diagnosis of intestinal obstruction secondary to an advanced rectosigmoid tumour. A request of two units packed RBC was made given anticipated blood loss intraoperatively. His pre-operative haemoglobin was 135 g/L. His previous immunohaematological record showed that he had an extremely rare P2k (P1-, P-, Pk+) phenotype with clinically significant anti-P, anti-PX2, and anti-P1. The elements of PBM strategies were explored and applied. Eventually, the patient successfully underwent a surgical operation without any allogeneic RBC transfusion.
- Full text:11.2019my0559.pdf
