Efficacy of severe intrauterine adhesions
10.16571/j.cnki.1008-8199.2020.06.012
- VernacularTitle: COOK球囊放置时长对重度宫腔粘连疗效的影响
- Author:
Wei-wei ZENG
1
;
Sheng-mei SU
1
;
Kai YAN
1
;
Yan GU
1
;
Zhen YUAN
1
;
Ji-long YAO
1
Author Information
1. Department of Gynecology, Shenzhen Maternity & Child Healthcare Hospital Affiliated to Southern Medical University, Shenzhen 518028,Guangdong, China
- Publication Type:Journal Article
- Keywords:
intrauterine adhesions;
transcervical resection of adhesion;
COOK balloon;
placement time;
pregnancy rate
- From:
Journal of Medical Postgraduates
2020;33(6):618-622
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the effect of COOK balloon placement time on the efficacy of severe intrauterine adhesions.Methods150 patients with severe IUA were prospectively enrolled and randomized divided into three short-term group, medium-term group and long-term group, with respectively balloon placement time 1 week, 1 month and 2 months. All subjects underwent transcervical resection of adhesion (TCRA). Re-adhesion and pregnancy rate after treatment, the relevant infection indicators, uterine cavity recovery, AFS score improvement rate, menstrual improvement, and endometrial thickness were analyzed.ResultsAll patients underwent transcervical resection of adhesion (TCRA) and COOK balloon placement successfully. Improvement of pregnancy rate and first pregnancy time were observed in group B and C than group A (P<0.05). The total effective rate of 12 months after treatment of group B (84.00%) and group C (86.00%) was better than group A (64.00%) (P<0.05). The positive rate of microbial culture of COOK balloon when took out at the second-look showed highest in group C (48.00%, P<0.05), followed by group B (30.00%) and group A (24.00%). The rate of uterine recovery of group B (82.00%) and C (78.00%) was better than group A (56.00%) (P<0.05). There were more patients with AFS score improvement in group B and C than group A (P<0.05). Similar improvement of menstrual and increasing of endometrium thickness were observed at the 6th and 12th months in group B and C after operation (P>0.05).ConclusionPlacement of the uterine COOK balloon for more than 1 month may improve uterine cavity, pregnancy rate, AFS score, menstruation and endometrial thickness. However, the risk of infection increased at the second month after COOK balloon placement.
