Construction of the animal model of mandibular severe alveolar bone atrophy in Beagle dogs
10.12016/j.issn.2096-1456.2017.08.005
- Author:
LV Yingtao
1
;
SU Yuan
2
;
MA Weiqun
3
;
LIU Shuying
3
;
XU Pingping
3
Author Information
1. Department of Oral Implantology Stomatological Hospital Southern Medical University
2. Department of Implantrestoration Stomatological Hospital Southern Medical University
3. Department of Oral and Maxillofacial surgery Stomatological Hospital Southern Medical University
- Publication Type:Journal Article
- Keywords:
Alveolar bone atrophy;
Animal model;
Vertical bone augmentation
- From:
Journal of Prevention and Treatment for Stomatological Diseases
2017;25(8):498-500
- CountryChina
- Language:Chinese
-
Abstract:
Objective :To establish an animal model that clinically conforms to the characteristics of severe alveolar ridge atrophy.
Methods :Beagle dogs were used as experimental subjects. Bilateral fourth premolars and first molars in mandible were extracted. A horizontal groove was made on alveolar ridge which was 8 mm from the cemento-enamal junction of mandible third premolar and second molar. Rongeur was used to remove the alveolar bone above this groove and bone chisel was used to level the bone-free area. A box-shaped defect cavity of the size 25 mm × 8 mm was formed with sterile silicone prosthesis implanted. After careful suture we waited for the subjects to heal naturally. Eight weeks after operation, CBCT examination was performed.
Results :Eight weeks after bone remodeling the top of alveolar ridge of operation area appeared to be a circular arc. The average distance from the bottom of the ridge to inferior alveolar nerve canal was 2.5 mm.
Conclusion :This study successfully established the Beagle dog animal model for severe alveolar ridge atrophy and laid the foundation for experiments on vertical bone augmentation.
- Full text:Beagle 犬下颌重度牙槽嵴萎缩动物模型的建立.pdf
