Research progress on indanomycin natural products
10.12206/j.issn.1006-0111.201910034
- VernacularTitle:茚满霉素类天然产物的研究进展
- Author:
Yuqin ZHU
1
;
Jiequn WU
1
;
Peng SUN
2
Author Information
1. Zhejiang University of Technology, Hangzhou 310014, China.
2. School of Pharmacy, Naval Medical University, Shanghai 200433, China.
- Keywords:
indanomycin;
indane ring;
biological activity;
chemical synthesis;
biosynthesis
- From:
Journal of Pharmaceutical Practice
2020;38(3):211-215
- CountryChina
- Language:Chinese
-
Abstract:
Indanomycins are a class of secondary metabolites of microorganisms with a trans-tetrahydroindan (indane) ring. These compounds generally have good antibacterial, insecticidal and antitumor biological activities, which have caused wide interest for medicinal chemists and biologists. This review summarizes the research progress of the discovery, biological activity, chemical synthesis and biosynthesis of indanomycin compounds since 1979 and provides scientific reference for the research and development of indanomycin antibiotics.
