The analysis of expression of HAase in oral squamous cell carcinoma
10.12016/j.issn.2096-1456.2017.10.005
- Author:
WANG Jingxu
1
;
LIAO Guiqing
2
Author Information
1. Department of Stomatology Guanzhou Medical University
2. Department of Oral and Maxillofaial Surgery Guanghua Shool of Stomatology Sun Yet-sen University
- Publication Type:Journal Article
- Keywords:
Oral;
Squamous cell carcinoma;
Hyaluronidase;
Tumor;
Immunohistochemistry
- From:
Journal of Prevention and Treatment for Stomatological Diseases
2017;25(10):638-640
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the expression of HAase in Oral Squamous Cell Caricinoma (OSCC).
Methods : The distribution and expression of HAase in 21 patients with OSCC and their resecetions with tumor-free margins were examined by immunohistochemistry method.
Results:HAase were mainly immunostained in tumor tissue. The expression of HAase in oral cancer with nodal metastasis and low pathological grades were higher than that with no nodal metastasis and high pathological grades (P < 0.05), whereas no difference between the TNM stages (P > 0. 05).
Conclusion :The HAase levels were high in oral squamous cell carcinoma tissues, and rising in patients with lymph node metastasis and poorly differentiated.
- Full text:透明质酸酶在口腔鳞癌组织中的表达及其临床意义.pdf
