Oral Manifestation and Caries Experience in Pre-Dialysis Chronic Kidney Disease Patients
10.21315/aos2019.14.2.394
- Author:
Nur Karyatee Kassim
1
Author Information
1. School of Dental Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia
- Collective Name:Loo Wan Feun; Siti Lailatul Akmar Zainuddin; Azreen Syazril Adnan; Hanim Afzan Ibrahim
- Publication Type:Journal Article
- Keywords:
Chronic kidney disease;
pre-dialysis;
oral manifestation;
caries experience
- From:Archives of Orofacial Sciences
2019;14(2):157-168
- CountryMalaysia
- Language:English
-
Abstract:
Patients with chronic kidney disease (CKD) are prone to develop oral lesions due to the disease process
or the therapy or both. The systemic problems started to develop in the pre-dialysis stages of CKD. Oral
lesions and caries experience are the non-traditional risk factors in progression of CKD. This research
was conducted to study and compare the oral manifestation and caries experience of pre-dialysis patients
and healthy subjects in Hospital Universiti Sains Malaysia (HUSM). Fifty-eight patients, which consist
of 29 pre-dialysis patients and 29 controls were recruited. CKD patients (stage III and IV) who attended
nephrology clinic and CKD Resource Centre Unit of HUSM were selected. The control group consisted
of healthy patients without any systemic disease who attended dental clinic of HUSM. The patients
were examined for the oral manifestation. The decayed, missing, filled teeth (DMFT) index were also
recorded. Oral lesions were present in 96.6% of pre-dialysis patients and 51.7% of control group (p <
0.001). The significant oral manifestations in pre-dialysis patients were xerostomia, halitosis, abnormal
taste, mucosa pallor, enamel hypoplasia, gingival enlargement and abnormal lip pigmentation. There
was significant difference in caries experience between pre-dialysis patients and healthy controls but
no correlation between estimated glomerular filtration rate (eGFR) and caries experience in the predialysis patients. Thus, dental screening needs to be done to control the problems. Future studies with
multicentred and larger sample size are warranted to explore the magnitude of this problem.
- Full text:2.2019my0181.pdf
